. 2017 Nov 13;5(2):128–134. doi: 10.1016/j.ijvsm.2017.10.002

Table 3.

Wound histologic indices and inflammatory cell counts of electroscalpel and cold scalpel induced wounds in rats at day 5, 7 and 14.

Parameters	Electroscalpel			Cold scalpel
Parameters	SSD	CONTROL	HONEY	SSD	CONTROL	HONEY
Day 5
Granulation tissue	3.00 ± 0.10^a	3.00 ± 0.20^a	3.00 ± 0.13^a	3.00 ± 0.20^a	3.00 ± 0.30^a	2.00 ± 0.10^a
Vascularization	2.00 ± 0.06^a	2.00 ± 0.10^a	2.00 ± 0.11^a	2.00 ± 0.06^a	2.00 ± 0.10^a	1.00 ± 0.07^a
Fibro-elastic tissue	0.00 ± 0.00^a	0.00 ± 0.00^a	0.00 ± 0.00^a	0.00 ± 0.00^a	0.00 ± 0.00^a	0.00 ± 0.00^a
Epithelialization	0.00 ± 0.00^a	0.00 ± 0.00^a	1.00 ± 0.01^a	0.00 ± 0.00^a	0.00 ± 0.00^a	2.00 ± 0.10^a
Macrophages	20 ± 8.49^a	43.0 ± 11.31^b	27.50 ± 2.12^a	7.5 ± 3.54^a	15.0 ± 21.21^a	29.5 ± 4.95^b
Neutrophils	16.5 ± 0.71^a	28.5 ± 0.71^b	20.50 ± 3.54^a	2.5 ± 3.54^a	8.5 ± 12.02^a	19.0 ± 24.0^a
Lymphocytes	15.0 ± 1.41^a	21.0 ± 16.97^a	32.00 ± 4.24^b	10.5 ± 2.12^a	20.0 ± 28.3^a	31.0 ± 7.1^a
Mast cells	3.0 ± 4.24^a	0.0 ± 0.00^b	6.00 ± 5.66^c	10.5 ± 6.4^c	0.00 ± 0.00^b	0.0 ± 0.00^b
Fibroblast	200 ± 28.5^a	78.0 ± 14.14^b	200 ± 15.80^a	10.0 ± 4.2^c	66.0 ± 77.8^b	200.0 ± 25.0^a

Day 7
Granulation tissue	1.00 ± 0.03^a	3.00 ± 0.30^b	3.00 ± 0.20^b	3.00 ± 0.10^b	2.00 ± 0.10^a	1.00 ± 0.04^a
Vascularization	1.00 ± 0.10^a	2.00 ± 0.10^a	1.00 ± 0.10^a	2.00 ± 0.08^a	1.00 ± 0.03^a	1.00 ± 0.08^a
Fibro-elastic tissue	2.00 ± 0.10^a	0.00 ± 0.00^b	0.00 ± 0.00^b	0.00 ± 0.00^b	0.00 ± 0.00^b	1.00 ± 0.03^a
Epithelialization	1.00 ± 0.05^a	0.00 ± 0.00^a	3.00 ± 0.20^b	1.00 ± 0.06^a	2.00 ± 0.10^b	2.00 ± 0.20^b
Macrophages	9.50 ± 4.94^a	18.0 ± 4.24^b	14.50 ± 14.85^a	27.5 ± 7.8^b	23.3 ± 9.89^b	16.5 ± 9.19^a
Neutrophils	7.50 ± 7.77^a	7.0 ± 5.65^a	2.50 ± 3.53^a	11.5 ± 7.78^a	9.5 ± 3.54^a	6.5 ± 9.19^a
Lymphocytes	20.0 ± 25.5^a	15.0 ± 2.82^a	11.00 ± 11.31^a	19.5 ± 0.71^a	21.0 ± 11.3^a	23.5 ± 23.3^b
Mast cells	7.00 ± 4.24^a	0.0 ± 0.00^b	0.00 ± 0.00^b	0.00 ± 0.00^b	0.00 ± 0.00^b	0.00 ± 0.00^b
Fibroblast	30.5 ± 20.5^a	37.0 ± 19.8^a	116.5 ± 118.1^b	146.5 ± 76^b	156.0 ± 0.0^b	62.2 ± 21.0^b

Day 14
Granulation tissue	0.00 ± 0.00^a	2.00 ± 0.20^b	1.00 ± 0.01^a	0.00 ± 0.00^a	0.00 ± 0.00^a	0.00 ± 0.00^a
Vascularization	1.00 ± 0.10^a	2.00 ± 0.08^b	1.00 ± 0.10^a	0.00 ± 0.00^a	0.00 ± 0.00^a	0.00 ± 0.00^a
Fibro-elastic tissue	2.00 ± 0.20^a	0.00 ± 0.00^b	2.00 ± 0.10^a	2.00 ± 0.10^a	2.00 ± 0.10^a	3.00 ± 0.20^a
Epithelialization	2.00 ± 0.10^a	1.00 ± 0.05^b	3.00 ± 0.20^a	3.00 ± 0.10^a	3.00 ± 0.20^a	3.00 ± 0.10^a
Macrophages	21.0 ± 18.4^a	18.0 ± 2.83^a	18.00 ± 2.83^a	36.5 ± 14.9^b	24.5 ± 4.95^a	13.0 ± 11.3^a
Neutrophils	10.0 ± 14.1^a	27.0 ± 24.04^b	2.00 ± 2.83^a	8.0 ± 5.7^a	10.5 ± 2.12^a	3.5 ± 4.95^a
Lymphocytes	29.0 ± 12.7^a	21.0 ± 1.31^a	37.50 ± 21.9^b	35.5 ± 6.4^b	26.0 ± 4.24^a	16.5 ± 2.1^a
Mast cells	3.50 ± 5.0^a	0.0 ± 0.00^a	0.00 ± 0.00^a	5.5 ± 7.8^a	2.5 ± 3.54^a	0.5 ± 0.71^a
Fibroblast	113.5 ± 60^a	114.5 ± 108.2^a	147.50 ± 74.3^a	200.0 ± 0.0^b	129.5 ± 99.7^a	94. ± 11.3^a

Values with different superscript are significant across rows at α = 0.05.

SSS = Silver sulphadiazine.