Table 3.
Comparison of diagnostic values between PET/CT using the optimized cut-off values and the fixed cut-off value of 2.5 in patients imaged by PET A and B
| Groups | Cut-off values | Sensitivity (%) | Specificity (%) | PPVa (%) | NPVb (%) | Accuracy (%) | AUCc | p |
|---|---|---|---|---|---|---|---|---|
| PET A | ||||||||
| Overall | 2.5 | 36.7 | 98.0 | 91.7 | 71.6 | 74.7 | 0.673 | 0.169 |
| Opt | 76.7 | 77.6 | 67.6 | 84.4 | 77.2 | 0.771 | ||
| Small LN | 2.5 | 18.8 | 100.0 | 100.0 | 74.5 | 75.9 | 0.594 | 0.047 |
| 1.1 | 87.5 | 73.7 | 58.3 | 93.3 | 77.8 | 0.806 | ||
| Large LN | 2.5 | 57.1 | 90.9 | 88.9 | 62.5 | 72.0 | 0.740 | 0.866 |
| 2.1 | 78.6 | 72.7 | 78.6 | 72.7 | 76.0 | 0.756 | ||
| PET B | ||||||||
| Overall | 2.5 | 35.1 | 96.7 | 86.7 | 70.7 | 73.2 | 0.659 | 0.520 |
| Opt | 75.7 | 65.0 | 57.1 | 81.3 | 69.1 | 0.703 | ||
| Small LN | 2.5 | 18.8 | 100.0 | 100.0 | 78.7 | 79.7 | 0.594 | 0.110 |
| 1.0 | 93.8 | 60.4 | 44.1 | 96.7 | 68.8 | 0.771 | ||
| Large LN | 2.5 | 47.6 | 83.3 | 83.3 | 47.6 | 60.6 | 0.655 | 0.162 |
| 1.9 | 61.9 | 83.3 | 86.7 | 55.6 | 69.7 | 0.726 | ||
aPPV positive predictive value
bNPV negative predictive value
cAUC area under the curve
dOpt optimal cut-off values of SUVmax