Table 4.

Stratified analysis of SNPs in a recessive model

SNPs	Group	Genotype	Duration of noise exposed work (years)		Expose level with noise (dB)
			≤ 16	>  16	≤ 85	85–92	>  92
rs3124594	case	GG	217	261	212	96	170
		AG/AA	20	37	31	9	17
	control	GG	183	231	189	73	152
		AG/AA	67	54	43	22	56
	P a		< 0.001	0.03	0.083	0.004	0.001
	Adjusted OR		4.20	1.67	1.55	3.29	3.65
	(95% CI)b		(2.44–7.24)	(1.06–2.63)	(0.94–2.57)	(1.40–7.71)	(2.03–6.57)
rs3124599	case	AA	98	125	97	40	86
		AG/GG	139	173	146	65	101
	control	AA	102	100	98	32	72
		AG/GG	148	185	134	63	136
	P a		0.902	0.089	0.607	0.516	0.021
	Adjusted OR		1.05	1.36	0.91	1.29	1.59
	(95% CI)b		(0.73–1.51)	(0.97–1.90)	(0.63–1.32)	(0.71–2.33)	(1.06–2.39)
rs3124603	case	CT/TT	68	72	70	27	43
		CC	169	226	173	78	144
	control	CT/TT	47	58	38	21	46
		CC	203	227	194	74	162
	P a		0.010	0.269	0.001	0.551	0.835
	Adjusted OR		1.73	1.24	2.06	1.19	1.08
	(95% CI)b		(1.13–2.66)	(0.84–1.84)	(1.32–3.22)	(0.61–2.31)	(0.67–1.75)

^aTwo-sided χ² test

^bAdjusted for age, sex, alcohol and tobacco use in a logistic regression model