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. 2018 Sep 14;11:115. doi: 10.1186/s13045-018-0660-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — The expression and function of CLC-3 were inhibited after XRCC5 knockdown. a, b The expression of CLC-3 was inhibited after XRCC5 knockdown in SGC-7901 and BGC-823 cells, and the inhibition effect was rescued by CLC-3 overexpression. c–f The proliferation and clonogenicity of SGC-7901 and BGC-823 cells were attenuated after XRCC5 knockdown, and the attenuation effects were rescued by CLC-3 overexpression (n = 3). g, h The migration and invasion of SGC-7901 and BGC-823 cells were inhibited after XRCC5 knockdown, and the inhibition effects were similarly rescued by CLC-3 overexpression (n = 3). *P < 0.05, **P < 0.01