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. 2018 Sep 14;11:115. doi: 10.1186/s13045-018-0660-y

Table 1.

Correlations between CLC-3 expression and clinicopathological characteristics of GC patients

Variables N CLC-3 χ 2 P value
Low
expression
High
expression
Age
 ≤ 70 55 29 26 0.014 0.904
 > 70 35 18 17
Gender
 Male 70 35 35 0.623 0.430
 Female 20 12 8
Pathological grade
 I/II 24 15 9 1.386 0.239
 III/IV 66 32 34
Depth of invasion
 T1/T2 11 10 1 7.517 0.006
 T3/T4 79 37 42
Lymph node metastases
 N0 23 17 6 5.826 0.016
 N1/N2/N3 67 30 37
Distant metastasis
 M0 86 45 41 0.009 0.927
 M1 4 2 2
TNM stage
 I/II 37 25 12 5.930 0.015
 III/IV 53 22 31

CLC-3 chloride channel-3, GC gastric cancer