Table 4.
Associations of XbaI genotypes with various clinical characteristics
| Variables | AA (n = 74) | AG (n = 154) | GG (n = 76) |
|---|---|---|---|
| Age (years) | 62.14 ± 4.24 | 63.24 ± 4.85 | 63.11 ± 3.75 |
| BMI (kg/m2) | 22.97 ± 2.99 | 23.98 ± 3.40* | 24.71 ± 3.18* |
| Waist circumference (cm) | 84.26 ± 5.36 | 84.92 ± 5.13 | 86.07 ± 4.96* |
| FBG (mM) | 4.95 ± 0.88 | 5.21 ± 1.41* | 5.70 ± 1.10*# |
| HbA1C (%) | 5.89 ± 1.00 | 5.94 ± 1.05 | 6.09 ± 0.98 |
| Systolic blood pressure (mmHg) | 132.31 ± 14.39 | 134.15 ± 13.96 | 139.05 ± 14.12*# |
| Diastolic blood pressure (mmHg) |
79.95 ± 11.96 | 81.14 ± 11.39 | 85.86 ± 10.69*# |
| Triglycerides (mM) | 1.84 ± 0.92 | 2.08 ± 1.20* | 2.38 ± 1.16* |
| Total cholesterol (mM) | 4.29 ± 1.20 | 4.72 ± 0.83* | 5.53 ± 1.12*# |
| HDL-C (mM) | 1.25 ± 0.26 | 1.15 ± 0.21* | 1.06 ± 0.20*# |
| LDL-C (mM) | 2.74 ± 0.64 | 2.83 ± 0.67 | 3.39 ± 0.83*# |
| NAFLD (%) | 28 (37.8) | 70 (45.5) | 45 (59.2)* |
| Fasting serum insulin (μIU/mL) |
11.15 ± 5.68 | 11.54 ± 6.23 | 12.54 ± 8.31 |
| Estradiol (pg/ml) | 26.82 ± 6.99 | 24.66 ± 7.48 | 24.49 ± 7.67 |
| HOMA-IR | 2.47 ± 1.32 | 2.72 ± 1.77* | 3.20 ± 1.70* |
Measurement data are mean ± SD, and were assessed by one way ANOVA with post-hoc SNK test
*Significant difference from patients harboring AA (p < 0.05)
#Significant difference from patients harboring AG (p < 0.05). Enumeration count data were described as rate, and assessed by the chi-square test