Table 4.

PD-L1 immunohistochemistry (IHC) scoring definition on tumor cell (TC) and immune cell (IC) compartments, as reported in clinical studies from the randomized Phase II trial POPLAR in 201617

PD-L1 TC scoring		PD-L1 IC scoring
Score	Percentage of PD-L1 expressing cells	Score	Percentage of PD-L1 expressing cells
TC3	≥50	IC3	≥10
TC2	≥5 and <50	IC2	≥5 and <10
TC1	≥1 and <5	IC1	≥1 and <5
TC0	<1	IC0	<1