Table 6.
F. prausnitzii, its phylogroups and A. muciniphila abundances in inflammatory bowel disease patients by age of disease onset.
| Diagnostics§ | n | F. prausnitzii* | P-value | Phylogroup I* | P-value | Phylogroup II* | P-value | A. muciniphila*# | P-value |
|---|---|---|---|---|---|---|---|---|---|
| UC | |||||||||
| 17–40 years (A2) | 11 | 4.87 ± 0.47 | 0.676 | 2.52 ± 1.09 | 0.171 | 3.12 ± 0.88 | 0.305 | 2.93 ± 1.19 | 0.569 |
| >41 years (A3) | 9 | 4.64 ± 0.91 | 1.65 ± 1.42 | 2.58 ± 1.10 | 2.88 ± 1.07 | ||||
| CD | |||||||||
| <16 years (A1) | 5 | 3.62 ± 1.59 | 0.004 ± 0.44 | 1.65 ± 1.71 | 1.76 ± 0.73a | ||||
| 17–40 years (A2) | 21 | 4.26 ± 1.36 | 0.562 | 1.40 ± 1.87 | 0.112 | 1.30 ± 1.34 | 0.547 | 3.31 ± 1.16b | 0.030 |
| >41 years (A3) | 3 | 4.67 ± 0.71 | 0.97 ± 0.48 | 2.26 ± 1.47 | 4.20 ± 2.15b | ||||
*
Median (log10 16S rRNA gene copies/million bacterial 16S rRNA gene copies) ± standard deviations.
§
UC, ulcerative colitis; CD, Crohn's disease.
#
Statistics was calculated separately for each variable (column). Groups of patients with similar abundances of A. muciniphila are indicated with the same superscript (a, b) whereas groups not sharing superscript are those with statistically different median abundance values (P < 0.05). Analyses statistically significant are highlighted in boldface.