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. 2018 Aug 8;6:232–246. doi: 10.1016/j.isci.2018.08.002

Figure 1.

Figure 1

Myogenic Reprogramming of Human Fibroblasts

(A) Time course of MYOD1-mediated reprogramming. The time window outlined in green corresponds to time points at which both genome architecture and transcription were captured by Hi-C (single replicates) and RNA-seq (in triplicate).

(B) Scale-adaptive Hi-C matrices and gene expression. The considered scales include 1 Mb, 100 kb, TAD, and gene level.