Myogenic Reprogramming of Human Fibroblasts
(A) Time course of MYOD1-mediated reprogramming. The time window outlined in green corresponds to time points at which both genome architecture and transcription were captured by Hi-C (single replicates) and RNA-seq (in triplicate).
(B) Scale-adaptive Hi-C matrices and gene expression. The considered scales include 1 Mb, 100 kb, TAD, and gene level.