TABLE 1.
Representative Mycobacterial Interspersed Repetitive Units – Variable Number of Tandem Repeats patterns for the dassie bacillus, Mycobacterium mungi, Mycobacterium suricattae and Mycobacterium africanum.
| Genomic locus | MIRU-VNTR repeat number† | |||
|---|---|---|---|---|
|
| ||||
| M. mungi | M. suricattae | Dassie bacillus | M. africanum | |
| MIRU 2 | 2 | 2 | 2 | 2 |
| VNTR 424/Mtub04 | 3 | 3 | 2 | 4 |
| VNTR 577/ETR-C | 3 | 5 | 5 | 5 |
| MIRU 4/ETR-D | 3 | 2 | 3 | 2 |
| MIRU 40 | 1 | 2 | 2 | 2 |
| MIRU 10 | 5 | 6 | 7 | 7 |
| MIRU 16 | 3 | 2 | 3 | 4 |
| VNTR 1955/Mtub21 | 3 | 3 | 3 | 4 |
| MIRU 20 | 2 | 2 | 2 | 2 |
| VNTR 2163b/QUB11b | 0 | - | 7 | 5 |
| VNTR 2165/ETR-A | 6 | - | 6 | 6 |
| VNTR 2347/Mtub29 | 3 | 3 | 3 | 3 |
| VNTR 2401/Mtub30 | 4 | 4 | 3 | 4 |
| VNTR 2461/ETR-B | 4 | 5 | 4 | 4 |
| MIRU 23 | 4 | 4 | 4 | 4 |
| MIRU 24 | 2 | 3 | 2 | 2 |
| MIRU 26 | 4 | 4 | 5 | 4 |
| MIRU 27 | 3 | 1 | 4 | 3 |
| VNTR 3171/Mtub 34 | 3 | 3 | 3 | 3 |
| MIRU 31/ETR-E | 8/9 | 5 | 5 | 5 |
| VNTR 3690/Mtub 39 | - | 8 | 5 | 4 |
| VNTR 4052/QUB 26 | - | 3 | 4 | 6 |
| VNTR 4156/QUB 4156 | - | 1 | 3 | 3 |
| MIRU 39 | 2 | 2 | 2 | 2 |
Source: Reproduced from Parsons, S.D.C., Drewe, J.A., Gey van Pittius, N.C., Warren, R.M. & Van Helden, P.D., 2013, ‘Novel cause of tuberculosis in meerkats, South Africa’, Emerging Infectious Diseases 19, 2004–2007, with permission from Emerging Infectious Diseases
Note: These patterns allow for genetic differentiation between these strains.
M., Mycobacterium; MIRU-VNTR, Mycobacterial Interspersed Repetitive Units – Variable Number of Tandem Repeats.
†
The number of repeats of genetic copies at the corresponding genomic locus.