TABLE 1.
Parameter | Unit | Thiafentanil-medetomidine |
Etorphine-medetomidine |
p-value (t-tests) | ||||
---|---|---|---|---|---|---|---|---|
Mean | ± s.d. | Range | Mean | ± s.d. | Range | |||
Clinical examination measurements | ||||||||
Temperature | °C | 38.9 | ±1.1 | 37.6–40.8 | 39.3 | ±0.7 | 38.2–40.6 | 0.341 |
Heart Rate | Beats/min | 122 | ±40 | 71–197 | 79 | ±37 | 45–150 | 0.032 |
Respiratory Rate | Breaths/min | 9 | ±5 | 2–15 | 9 | ±2 | 2–13 | 0.818 |
Minute volume | L/min | 8.9 | ±4.7 | 2.4–14.3 | 8.0 | ±3.2 | 3.5–14.0 | 0.659 |
MAP | mmHg | 126 | ±14 | 108–152 | 117 | ±18 | 94–133 | 0.226 |
Clinical pathology measurements and calculations | ||||||||
PaO2 | mmHg | 47 | ±8 | 38–62 | 41 | ±12 | 24–55 | 0.193 |
kPa | 6.3 | ±1.1 | 5.1–8.3 | 5.5 | ±1.6 | 3.2–7.3 | ||
PaCO2 | mmHg | 51 | ±9 | 38–68 | 51 | ±7 | 45–63 | 0.952 |
kPa | 6.8 | ±1.2 | 5.1–9.1 | 6.8 | ±0.9 | 6.0–8.4 | ||
PETCO2 | mmHg | 41 | ±7 | 29–52 | 51 | ±7 | 41–64 | 0.019 |
kPa | 5.5 | ±0.9 | 3.9–6.9 | 6.8 | ±0.9 | 5.5–8.5 | ||
PaCO2-PETCO2 | mmHg | 10 | ±9 | (-4)–23 | 0 | ±8 | (-11)–12 | 0.028 |
P(A-a)O2 | mmHg | 31 | ±7 | 19–40 | 38 | ±8 | 29–48 | 0.078 |
Lactate | mmol/L | 2.2a | (1.8–4.9)a | 1.4–5.4 | 2.2a | (1.9–4.2)a | 1.2–5.3 | 0.637b |
Cortisol | nmol/L | 84.5 | ±41.9 | 35.6–173.0 | 80.0 | ±37.7 | 21.8–136.0 | 0.817 |
s.d., standard deviation; °C, degree Celsius; min, minute; MAP, mean arterial blood pressure; mmHg, millimetres mercury; kPa, kilopascals; PaO2, arterial oxygen tension; PaCO2, arterial carbon dioxide tension; PETCO2, end-tidal carbon dioxide tension; PaCO2-PETCO2, arterial-to-end-tidal carbon dioxide tension gradient; P(A-a)O2, alveolar-to-arterial oxygen tension gradient; mmol, millimoles; nmol, nanomoles.
median and (interquartile range); b, p-value for Moods Median Test.