TABLE 1.

Study schedule or tabulated timeline summary to elucidate actions performed on the days indicated.

Actions performed	Days
Acclimatisation	Dogs were housed in the facility at least 7 days prior to Day 0
Artificial infection	Prior to Day 0
Administration of IVP	Days 0 to +19
	Days +58 to +85 (4 dogs)
	Days +73 to +100 (1 dog)
Platelet counts	Prior to infection and Days −1, +14, +28, +56, +63, +70, +71, +77, +84, +85, +86, +99, +100, 113/+114, +127, +128, +139, +155, +169, +170 and +184
Blood collection for PCR	Prior to infection and Days −1, +14, +28, +56, +70, +71, +84, +85, +86, +99/+100, +127, +139, +143, +155, +169 and +184
Blood collection for IFA	Prior to infection and Days −1, +14, +28, +56, +84, +85 and +100
Body weight	Days −1, +58, +70, +100, +113, +114, +157, +169 and +184
Clinical examinations	Prior to infection, Day −1 and Days +3, +14, +28, +56, +71, +84, +85, +86, +99, +100, +113, +114, +127, +128, +139, +155, +169, +170 and +184
Body temperature monitoring	Days 0 to +19
	Days +58 to +84
	Days +73 to +100
	Days +141 to +161

Note: Day 0 was defined as the day that an infection with Ehrlichia canis was confirmed by polymerase chain reaction analysis.

IVP, Investigational veterinary product; PCR, polymerase chain reaction; IFA, immunofluorescence assay.