Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
C-statistic calculated for predictive models based on biomarker measurement.
| Model | AUC | IDI | p |
|---|---|---|---|
| Model 1 (OSN alone) | 0.918 | – | – |
| Model 2 (NT-pro-BNP alone) versus Model 1 | 0.865 | 0.031 | 0.38 |
| Model 3 (OSN + NT-pro-BNP) versus Model 1 | 0.961 | 0.035 | 0.42 |
Abbreviations: IDI: index discrimination improvement; CI: confidence interval; AUC: area under curve; OSN: osteonectin; NT-pro-BNP: N-terminal pro-brain natriuretic peptide.
