Figure 1. Effects of I _KAS blockade on APD at basal condition.

A and B, representative V _m traces, ΔAPD₂₅ and ΔAPD₈₀ maps in female (A) and male (B) rabbit ventricles at RA PCL 200, 250 and 300 ms under Protocol I. The apamin‐induced APD prolongation was less than 5% in the absence of β‐adrenergic stimulation. Representative V _m traces were obtained at the LV base. C, summary data showed that no significant difference existed in ΔAPD₂₅ and ΔAPD₈₀ between females and males at baseline (by two‐way ANOVA with Sidak's post hoc test). [Color figure can be viewed at http://wileyonlinelibrary.com]