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Effects of p75NTR and truncated TrkB knockdown on NT-4-induced MPZ expression. Knockdown of truncated TrkB expression significantly reduced the NT-4-induced MPZ expression (n = 5, p = 0.001), while knockdown of p75NTR expression did not change the expression of MPZ induced by NT-4 in SCs. A bar graph represents band intensities normalized to those for GAPDH. Each bar represents the mean ± SEM of five independent experiments. *p < .05; **p < .01, NS, not significant.
