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. 2017 Feb 21;21(2):84–92. doi: 10.1080/19768354.2017.1289980

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© 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 6. — Involvement of mTORC1 signaling in MPZ expression. Impact of rapamycin on MPZ expression in Schwann cells was determined by western blotting analysis. Rapamycin (50 μM, 2 h) pretreatment Schwann cells rapidly reduced the expression of MPZ induced by NT-4; however, SB216763 (40 μm, 2 h) did not affect MPZ expression in these cells. A bar graph represents band intensities normalized to those for GAPDH. Each bar represents the average ± SEM of independent experiments. *p < .05; **p < .01, NS, not significant.