Fig 1. Radiolabelled cholesterol accumulation in the plasma, liver and adipose tissue.

The concentration of radiolabelled cholesterol as percent of injected dose in (A) plasma over 48 h, (B) per gram of liver wet weight, (C) total liver protein, (D) per gram of adipose wet weight and (E) total adipose mass. A known volume of plasma (30 mL) was measured directly using liquid scintillation counting while lipids were extracted from tissue by Bligh-Dyer before quantifying. Values were then expressed as a % of the total amount of radiolabelled cholesterol injected. *p<0.0005, **p = 0.03.