Table 1. Plasma and liver lipids.

		Wildtype littermate	Ob/ob
Plasma Lipids (mmol/L)	TC	2.45 ± 0.10	4.20 ± 0.07*
	non-HDLc	0.91 ± 0.09	1.73 ± 0.08*
	HDLc	1.54 ± 0.12	2.47 ± 0.11*
	TG	1.086 ± 0.04	1.199 ± 0.03
n = 6	non-HDL TG	0.517 ± 0.03	0.646 ± 0.06
	HDL TG	0.455 ± 0.02	0.553 ± 0.04
	Glycerol nmol/ml	506 ± 57.16	448.3 ± 58.33
Liver (mmol/l/μg protein)	TC	0.80 ± 0.13	0.95 ± 0.25
n = 4	TG	1.50 ± 0.24	5.41 ± 0.34a

Plasma total cholesterol, HDL-c and non-HDL cholesterol concentrations, as well as plasma total triglyceride, free glycerol, HDL and non-HDL triglyceride were determined in 8-week old male ob/ob and wildtype littermate control mice using enzymatic methods. Liver TC and TG were determined from homogenised lysates using enzymatic kits and then normalised to protein concentrations. Values are mean ± S.E.M.

*p<0.0001

^ap<0.0001 vs Wildtype littermate control mice.