Table 1. Characteristics of patients based on pathological architectural features (n = 382).
| Micro-T (n = 266) |
PG (n = 33) |
Macro-T (n = 38) |
Compact (n = 43) |
P-value | |
|---|---|---|---|---|---|
| Gender Male | 206 (77%) | 29 (88%) | 26 (68%) | 35 (81%) | 0.2378 |
| Age† (years) | 68 | 68 | 64.5 | 67 | 0.3453 |
| AFP† (U/mL) | 11.1 | 12.2 | 651.5 | 52.9 | < .0001 |
| PIVKAII† (U/mL) | 62 | 188 | 600 | 200 | 0.0009 |
| Triple positive | 39 (15%) | 1 (3%) | 16 (42%) | 18 (42%) | < .0001 |
| ICG R15† (%) | 11.8 | 12.2 | 9.2 | 12.0 | 0.0921 |
| HCV-Ab (+) | 127 (48%) | 14 (44%) | 16 (43%) | 24 (55%) | 0.6553 |
| Albumin† (g/dl) | 4.0 | 4.0 | 4.1 | 3.9 | 0.3643 |
| Tumor size† (mm) | 32 | 34.5 | 52.5 | 40 | 0.0071 |
| Tumor number (solitary) | 183 (72%) | 25 (78%) | 21 (57%) | 23 (56%) | 0.0388 |
| Vascular invasion (+) | 81 (31%) | 10 (31%) | 25 (66%) | 26 (60%) | < .0001 |
| Gross morphology SN | 183 (72%) | 25 (78%) | 21 (57%) | 23 (56%) | 0.0388 |
| Liver cirrhosis‡ | 98 (37%) | 7 (21%) | 13 (34%) | 22 (51%) | 0.0614 |
Micro-T, microtrabecular; PG, Pseudoglandular; macro-T, macrotrabecular; SN, simple nodular, AFP; Alpha-fetoprotein, PIVKA-II; protein induced by Vitamin K absence or antagonists-II
† Median value
‡ Defined by F4 stage from new Inuyama classification (Ichida et al. Int Hepatol Commun 1996)