Table 2. Characteristics of patients based on pathological architectural subgroups (n = 382).
| Micro-T/PG (n = 299) |
Macro-T/C (n = 81) |
P-value | |
|---|---|---|---|
| Gender Male | 235 (79%) | 61 (75%) | 0.5272 |
| Age† (years) | 68 | 65 | 0.0695 |
| AFP† (U/mL) | 11.1 | 125.2 | < .0001 |
| DCP† (U/mL) | 68 | 279 | 0.0003 |
| Triple positive | 40 (13%) | 34 (42%) | < .0001 |
| ICG R15† (%) | 11.8 | 10.6 | 0.0878 |
| HCV-Ab (+) | 141 (48%) | 40 (50%) | 0.7461 |
| Albumin† (g/dl) | 4.0 | 4.0 | 0.6944 |
| Tumor size† (mm) | 32 | 45 | 0.0009 |
| Tumor number (solitary) | 221 (75%) | 50 (62%) | 0.0218 |
| Vascular invasion (+) | 91 (31%) | 51 (63%) | < .0001 |
| Gross morphology SN | 208 (73%) | 44 (56%) | 0.0049 |
| Liver cirrhosis‡ | 105 (35%) | 35 (43%) | 0.1943 |
Micro-T, microtrabecular; PG, Pseudoglandular; macro-T, macrotrabecular; AFP; Alpha-fetoprotein, des-c-carboxy prothrombin, DCP; SN, simple nodular,
† Median value
‡ Defined by F4 stage from new Inuyama classification (Ichida et al. Int Hepatol Commun 1996)