Medical |
1,292 |
73.6% |
4,581 |
82.7% |
<0.001 |
|
Abnormal PTT, PLT < 100K, INR > 1.3 |
34 |
1.9% |
122 |
2.2% |
0.503 |
|
Age < 18 or > 80 years |
98 |
5.6% |
884 |
16.0% |
<0.001 |
|
Aneurysm, mycotic aneurysm, moyamoya, etc. |
161 |
9.2% |
743 |
13.4% |
<0.001 |
|
Craniectomy/other surgical procedures |
21 |
1.2% |
51 |
0.9% |
0.308 |
|
Etiology - tumor |
3 |
0.2% |
47 |
0.8% |
0.003 |
|
GCS < 3/herniation/brain dead/deceased |
25 |
1.4% |
43 |
0.8% |
0.014 |
|
Historic (pre-bleed) Rankin not 0 or 1 |
47 |
2.7% |
96 |
1.7% |
0.013 |
|
ICH > 30 cc on diagnostic CTC |
256 |
14.6% |
700 |
12.6% |
0.035 |
|
Infratentorial bleed |
150 |
8.5% |
451 |
8.1% |
0.591 |
|
No EVD placed |
220 |
12.5% |
733 |
13.2% |
0.449 |
|
No obstruction of 3rd and/or 4th |
261 |
14.9% |
636 |
11.5% |
<0.001 |
|
Unstable bleeding |
16 |
0.9% |
75 |
1.4% |
0.146 |
|
Non-medical |
199 |
11.3% |
471 |
8.5% |
<0.001 |
|
Improper screening |
9 |
0.5% |
21 |
0.4% |
0.446 |
|
Participation in another trial |
6 |
0.3% |
10 |
0.2% |
0.208 |
|
Patient eligible but refused consent |
54 |
3.1% |
66 |
1.2% |
<0.001 |
|
Patient is DNR |
59 |
3.4% |
250 |
4.5% |
0.037 |
|
Study staff not notified within window |
11 |
0.6% |
21 |
0.4% |
0.171 |
|
Study staff unavailable |
2 |
0.1% |
8 |
0.1% |
0.764 |
|
Unable to dose within time window |
58 |
3.3% |
95 |
1.7% |
<0.001 |
|
Combination medical and non-medical reasons |
265 |
15.1% |
490 |
8.8% |
<0.001 |
|
MD/Surgeon chose not to enroll |
56 |
3.2% |
65 |
1.2% |
<0.001 |
|
Not an IVH patient |
18 |
1.0% |
49 |
0.9% |
0.59 |
|
Other |
191 |
10.9% |
376 |
6.8% |
<0.001 |
|
Total |
1,756 |
100.0% |
5,542 |
100.0% |
|