Qualitative evaluation for the detection of head and neck cancer in three mice. (a) RGB composite images generated from the tumor hypercube, (b) The detection results by the CNN based classification, (c) The final results refined by post-processing, and (d) the pair overlap between our detected result and the gold standard from the GFP images, where the white, black, pink, and green regions mean the true positive, true negative, false positive, and false negative regions, respectively.