Table 6.
Number and percentage (%) of replication-dependent histone peptides without (No) and with (Yes) acetylation post-translational modification (PTM) by genotype-treatment group and by histone cluster family.
| Histone | Genotype-treatmentb | Genotype-treatment | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| cluster | WT_ Sal | WT_ BCG | KO_ BCG | Total | % | WT_ Sal | WT_ BCG | KO_ BCG | Total | % | |
| Family member | No PTM | No PTM | No PTM | No PTM | No PTM | Yes PTM | Yes PTM | Yes PTM | Yes PTM | Yes PTM | Total |
| Total Hist 1 | 4028 | 3258 | 5150 | 12436 | 98% | 96 | 116 | 90 | 302 | 2% | 12738 |
| % Hist 1 | 83% | 78% | 84% | 86% | 85% | 89% | |||||
| Total Hist 2 | 727 | 803 | 822 | 2352 | 99% | 9 | 14 | 7 | 30 | 1% | 2382 |
| % Hist 2 | 15% | 19% | 13% | 8% | 10% | 7% | |||||
| Total Hist 3 | 39 | 32 | 56 | 127 | 100 % | 0 | 0 | 0 | 0 | 0% | 127 |
| % Hist 3 | 1% | 1% | 1% | 0% | 0% | 0% | |||||
| Hist 4 | 88 | 77 | 88 | 253 | 94% | 6 | 6 | 4 | 16 | 6% | 269 |
| % Hist 4 | 2% | 2% | 1% | 5% | 4% | 4% | |||||
| Total | 4882 | 4170 | 6116 | 15168 | 98% | 111 | 136 | 101 | 348 | 2% | 15516 |
a
Hist #: Histone # cluster
b
WT = wild type mice; KO = IDO1 KO mice; Sal = saline treatment; BCG = Bacillus Calmette–Guérin treatment.