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. Author manuscript; available in PMC: 2019 Sep 28.
Published in final edited form as: J Control Release. 2018 Aug 11;286:415–424. doi: 10.1016/j.jconrel.2018.08.018

Fig. 2. Fibrinogen increased the permeability of AAV9 in vitro.

Fig. 2.

Either fibrinogen, FN, vWF, or PBS was incubated with AAV9 at 4 °C for 2 hours, and were then transferred into the upper chamber of transwell with Caco-2 cells. At the time points of 30 minutes, 2-, 6-, and 24- hours, the media was collected from the lower chamber and was tested by qPCR for the AAV9 virus genome. The experiment was independently performed twice. Each experiment contained a 3-replicated transwell. A representative experiment is shown.