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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Mol Immunol. 2018 Jun 2;101:46–54. doi: 10.1016/j.molimm.2018.05.024

Figure 4. C-DIM12 decrease IκBα and p65 NF-κB Expression in Synovial Fibroblasts.

Figure 4

(a and c) The dose response of IκBα and NF-κB expression was determined 30 mins after TNFα (10 ng/ml). (b and d) synovial fibroblasts were stimulated with TNFα (10ng/ml) treated with 10μM CDIM12 analyzed by flow cytometry. Data are expressed as mean ± S.E.M (n=4). Statistical significance is compared with saline control. *P < 0.05, **P<0.01, ***P<0.001, ****P<0.0001.