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. Author manuscript; available in PMC: 2018 Nov 30.
Published in final edited form as: Oncogene. 2018 May 30;37(37):5054–5065. doi: 10.1038/s41388-018-0343-8

Figure 4. Inhibition of autophagy induced by downregulation of p14ARF is independent of p53 protein.

Figure 4

(A) Expression of p14ARF was downregulated with specific siRNA in HCT116 p53+/+ and HCT116 p53−/− cells. Cells were co-cultured with strain 7.13 (+) for the indicated time or left uninfected (−). LC3B and p14ARF proteins were analyzed by Western blotting. (B) Expression of LC3B-II protein was quantified by densitometry and normalized to actin levels. Graphs depict results as mean ± SEM, (*, p<0.05; **, p<0.01; n=2).