. Author manuscript; available in PMC: 2019 Oct 1.

Published in final edited form as: Crit Care Med. 2018 Oct;46(10):1585–1591. doi: 10.1097/CCM.0000000000003261

Table 2.

Reasons for SEP-1 Failure

Bundle Failure Reason	Number of Failures (%)^* (Total N=570)
Initial Lactate Not Drawn Within 3 Hours	112 (19.7%)

Blood Cultures Within 3 Hours (Not Drawn, or Drawn After Antibiotics)	86 (15.1%)

Antibiotics Within 3 Hours
Not Given	77 (13.5%)
Inappropriate Selection	12 (2.1%)

Repeat Lactate Not Drawn Within 6 Hours	116 (20.4%)

Crystalloids (Inadequate Amount or Not Given within 3 Hours)	104 (18.3%)

Persistent Hypotension Not Assessed After Crystalloid Fluids	4 (0.7%)

Vasopressors Not Given Within 6 Hours of Persistent Hypotension	8 (1.4%)

Volume Assessment Not Done within 6 Hours of Septic Shock	42 (7.4%)

The distribution includes only the first component of the SEP-1 bundle that failed in each case.