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. 2018 Apr 7;41(1):41–45. doi: 10.1016/j.bj.2018.01.001

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© 2018 Chang Gung University. Publishing services by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 4 — Histologic evaluation of liver tissue of the rats in different groups. H&E × 100.The liver sections of sodium bicarbonate group showed normal appearance and there were no changes in central vein and portal areas with no signs of inflammation or necrosis (A). In indomethacin treated rats, dilated expansion of hepatic sinusoids (arrow) and blood vessels in portal area (arrow head) and leucocytes infiltration (*) in these parts were noticed. Mild periportal hepatic necrosis was also seen (#) (B). In AEPOS pretreated rats, liver tissue showed normal structures and there were no changes in central vein and portal areas with no sign of necrosis (C).