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. 2018 Sep 14;8:13813. doi: 10.1038/s41598-018-32189-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Casp3 isn’t target of miR-199a-5p. (a) The alignment between Mus musculus miR-199a-5p and the 3-UTR of Casp3, identified by TargetScanS software. (b) qRT-PCR analysis of Casp3 mRNA expression levels in the PC12 cells following transfection. (c,d) Western blot analysis of Casp3 protein expression in PC12 cells following transfection. (full-length blots/gels are presented in Supplementary Fig. S8). (e) Comparison of luciferase activity in the NC and miR-199a-5p mimic groups. The values are expressed as the mean ± SD. *P < 0.05, **P < 0.01.