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. 2018 Sep 14;8:13801. doi: 10.1038/s41598-018-32257-w

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Group difference of gray matter density between CC and CN groups (3dClustSim correction, p < 0.001). (A) Brain regions showing gray matter atrophy in CC patients compared to CN subjects; (B) Numerical representation of significant difference in gray matter. Abbreviations: CC, breast cancer patients after chemotherapy; CN, cognitively normal subject; pCbm. L, left posterior cerebellum lobe; aCbm. R, right anterior cerebellum lobe; IFG.L, left interior frontal gryus; FFA.R, right fusiform area; MGF.R, right middle frontal gyrus.