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. 2018 Sep 14;9:3753. doi: 10.1038/s41467-018-05936-5

Table 1.

Goodness-of-fit statistics for mutation rate estimates applied to de novo testing data

Mutation rate estimation strategy AIC ΔAICa AIC rankb Nagelkerke’s R2
Subtype length Study Variant type
1-mers BRIDGES ERVs 353,896 21,575 7 0.088
3-mers BRIDGES ERVs 335,319 2998 4 0.118
5-mers BRIDGES ERVs 332,861 540 3 0.124
7-mers BRIDGES ERVs 332,321 0 1 0.126
7-mers BRIDGES ERVs (passing 1000G strict mask) 332,582 261 2 0.125
7-mers BRIDGES MAC10+ 342,886 10,565 5 0.103
7-mers 1000G Intergenic SNVs7 344,003 11,682 6 0.100

aDifference in AIC from the baseline BRIDGES 7-mer model

bLower AIC rank indicates better model performance