Table 1.

Patient characteristics.The different ¹³C-MBT readout groups did not differ significantly from each other with respect to age, height or weight. However, group 1 (>315.0 [µg/kg/h]) was significantly shorter (p < 0.05) and lighter (p < 0.05) than group 2 (140.0–315.0 [µg/kg/h]) and group 3 (<140.0 [µg/kg/h]).

parameter	n = 79	13C-MBT readout
		>315.0 [µg/kg/h] n = 20	140.0–315.0 [µg/kg/h] n = 36	<140.0 [µg/kg/h] n = 23
age [years]	61.85 ± 9.54	61.00 ± 11.64	63.03 ± 9.83	60.74 ± 6.92
male	62 (78.48%)	8 (40.0%)	33 (91.67%)	21 (91.30%)
female	17 (21.52%)	12 (60.0%)	3 (8.33%)	2 (8.70%)
height [cm]	173.19 ± 7.65	168.70 ± 9.10	174.86 ± 7.36	174.48 ± 5.03
weight [kg]	86.08 ± 16.06	78.70 ± 21.64	89.08 ± 13.14	87.78 ± 12.98
rrT1_in [%]	50.05 ± 13.55	60.99 ± 7.66	52.21 ± 10.87	37.16 ± 11.06
rrT1_W [%]	51.75 ± 13.66	63.14 ± 6.72	54.04 ± 10.86	38.27 ± 10.87
13C-MBT [µg/kg/h]	227.38 ± 122.24	396.85 ± 60.25	217.53 ± 50.26	95.44 ± 36.75

All groups were significantly different with respect to rrT1_in and rrT1_W (p < 0.001).

Values indicate means ± standard deviation.

rrT1_in: reduction rate of T1 relaxation time using in-phase T1 mapping.

rrT1_W: reduction rate of T1 relaxation time using water-only T1 mapping.

¹³C-MBT: liver function capacity estimated by breath analysis of ¹³C-labeled methacetin metabolism.