Table 1.

Generated Models of XAGE-1b using SWISS-MODEL tool with specific template for each assessed according to the parameters of SWISS-Model (sequence similarity, sequence Identity, GMQE, QMEAN4).

Property	Model A	Model B	Model C	Model D	Model E	Model F	Model G	Model H
Template PDB Acc. No.	4IFD	3U1K	2AE8	4JTU	1E3P	EJ43	2ZKQ	4PBN
Sequence Identity	42	38.3	32.39	32.2	30	28.57	28.17	25
Sequence similarity	0.4	0.38	0.36	0.38	0.37	0.34	0.35	0.36
GMQE	0.39	0.31	0.58	0.48	0.1	0.26	0.58	0.44
QMEAN4	−1.18	−6.25	−3.89	−5.21	−4.62	−2.22	−3.85	−3.44
Procheck G-factor e (phi/psi only	−0.76	−0.75	−1.45	−1.11	−1.00	−0.47	−1.03	−0.66
Procheck G-factor e (all dihedral angles)	−0.37	−0.28	−0.74	−0.62	−0.40	−0.01	−0.45	−0.23
Verify3D Score	0.02	0.07	0.12	0.05	−0.08	−0.09	−0.03	0.02
Most favored regions	78.4%	88.9%	63.3%	71.2%	79.6%	77.8%	80.0%	91.8%
Additionally allowed regions	21.6%	9.3%	30.6%	25.8%	20.4%	18.5%	17.1%	6.6%
Generously allowed regions	0.0%	0.0%	2.0%	3.0%	0.0%	3.7%	2.9%	0.0%
Disallowed region	0.0%	1.9%	4.1%	0.0%	0.0%	0.0%	0.0%	1.6%
Most favored regions	89.7%	93.5%	73.2%	85.5%	88.5%	90%	87.5%	91.5%
Allowed regions	6.9%	3.2%	19.6%	10.5%	9.8%	10%	10%	7%
Disallowed regions	3.4%	3.2%	7.1%	3.9%	1.6%	0%	2.5%	1.4%
RAMPAGE server Ramachandran plot	87.9%	91.9%	73.2%	84.2%	88.5%	90.0%	90.0%	88.7%