Table 2.
Results from the meta-analysis, pooled survival estimates and heterogeneity statistics
| Statistic | NPI 1 | NPI 2 | NPI 3 |
|---|---|---|---|
| 5-year follow-up | |||
| Fixed effects I-V estimate (95% CI) | 0.953 (0.949, 0.957) | 0.831 (0.825, 0.837) | 0.535 (0.521, 0.549) |
| Random effects D-L estimate (95% CI) | 0.943 (0.927, 0.96) | 0.811 (0.769, 0.853) | 0.565 (0.462, 0.668) |
| I2 (%) | 89.6 | 97.2 | 97.7 |
| Q | 115.93 (P < 0.001) | 422.5 (P < 0.001) | 532.32 (P < 0.001) |
| Tau (% points) | 2.45 | 7.28 | 18.25 |
| 10-year follow-up | |||
| Fixed effects I-V estimate (95% CI) | 0.883 (0.877, 0.888) | 0.682 (0.675, 0.689) | 0.353 (0.341, 0.364) |
| Random effects D-L estimate (95% CI) | 0.869 (0.837, 0.901) | 0.674 (0.608, 0.74) | 0.414 (0.329, 0.499) |
| I2 (%) | 95.3 | 98.6 | 97.7 |
| Q | 213.56 (P < 0.001) | 727.14 (P < 0.001) | 427.44 (P < 0.001) |
| Tau (% points) | 4.58 | 10.77 | 13.71 |
I-V inverse variance, D-L DerSimonian and Laird method