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. 2018 Sep 10;10:3357–3369. doi: 10.2147/CMAR.S169577

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© 2018 Motadi et al. This work is published by Dove Medical Press Limited, and licensed under a Creative Commons Attribution License

The full terms of the License are available at http://creativecommons.org/licenses/by/4.0/. The license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Relative quantification of gene expression in MCF-7 (A) and MD-MB-231 (B) cell lines performed using qPCR. Whisker box plots with expression ratio on the y-axis and gene type on the x-axis indicate quantification of mRNA isolated from cells treated with siRBBP6, pRBBP6, siRBBP6+camptothecin and siRBBP6+GABA. Gene expression is depicted by the color-coded whisker bars in the following manner: RBBP6 (red), TP53 (blue), bax (yellow), bak1 (light green), Bad (gray), caspase-3 (dark green), caspase-8 (cyan) and Bcl-2 (light blue).

Abbreviations: qPCR, quantitative PCR; GABA, γ-aminobutyric acid.

Relative quantification of gene expression in MCF-7 (A) and MD-MB-231 (B) cell lines performed using qPCR. Whisker box plots with expression ratio on the y-axis and gene type on the x-axis indicate quantification of mRNA isolated from cells treated with siRBBP6, pRBBP6, siRBBP6+camptothecin and siRBBP6+GABA. Gene expression is depicted by the color-coded whisker bars in the following manner: RBBP6 (red), TP53 (blue), bax (yellow), bak1 (light green), Bad (gray), caspase-3 (dark green), caspase-8 (cyan) and Bcl-2 (light blue).

Abbreviations: qPCR, quantitative PCR; GABA, γ-aminobutyric acid.