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Five classes of lncRNAs based on biogenesis. Sense lncRNAs overlap with coding genes on the same strand. Antisense lncRNAs overlap with protein-coding genes on the opposite strand. Intronic lncRNAs occur completely within an intron. Intergenic lncRNAs occur between two genes. Pseudogene lncRNAs are the product of reverse transcribed mRNA and inserted into genome. Adapted, with permission from [9].
