Skip to main content
. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Front Neuroendocrinol. 2018 May 18;50:52–66. doi: 10.1016/j.yfrne.2018.03.006

Figure 1. Distribution of animal sex reported in preclinical TBI studies in 2011 and 2016.

Figure 1

The majority of TBI studies in 2011 (80%) and 2016 (77%) used only male animals. Only a small proportion of studies in 2011 used both males and females (5%), which slightly increased to 7% in 2016. The search strategy included animal studies with the term traumatic brain injury or TBI for articles published in Pubmed between January 1st, 2011 and December 31st, 2011 (2011 graph); or January 1st, 2016 and December 31st, 2016 (2016 graph). Reviews, comments and retracted articles were excluded, as well as studies that used TBI as an abbreviation for total body irradiation. For 2011, 311 studies of TBI in an animal model are included, and 324 studies are included for 2016.