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. Author manuscript; available in PMC: 2019 Sep 15.
Published in final edited form as: Cancer Res. 2018 Aug 2;78(18):5431–5445. doi: 10.1158/0008-5472.CAN-17-3811

Fig. 4. RAB38 enhanced melanoma metastasis in vitro. (A).

Fig. 4

In vitro migration and invasion assays showed similar migration rates but significantly increased invasion rates in FLAG-RAB38-expressing WM-115 cells as compared to empty vector control. Migration and invasion capabilities were measured by using transwell migration and Matrigel-based invasion assays, respectively; (B) Quantification results for in vitro migration and invasion assay shown in panel (A). (C) In vitro migration and invasion assays showed similar migration rates but significantly decreased invasion rates for WM-266-4 cells with siRAB38 knockdown as compared to non-targeting siRNA control; (D) Quantification results for in vitro migration and invasion assay shown in panel (C). Error bars represent mean ± standard deviation (n = 3). The p values were calculated by using an unpaired, two-tailed Student’s t test.