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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: AIDS. 2019 Feb 1;33(2):163–184. doi: 10.1097/QAD.0000000000001796

Table 7.

Summary of key primary neurologic complications in children with HIV.

Complication Prevalence Key Studies
Progressive encephalopathy Untreated children: 30–50%
With early cART: <1%
Donald et al. 2015; Patel et al. 2009
Other cognitive impairment Untreated children: >90%
With early cART: 10–50%
Abubakar 2008; Nachman et al. 2009
Stroke Uncommon (exact prevalence unknown) Izbudak 2013; Shah et al. 1996
Seizures/Epilepsy 3–14% Samia et al. 2013; Bearden et al. 2015
Myelopathy Rare (exact prevalence unknown) Sharer et al. 1990
Peripheral neuropathy 5–50% Floeter et al. 1997; Peters et al. 2014