Table 1.
Inclusion criteria | Exclusion criteria |
---|---|
Age 70 to 85 | Severe chronic condition or medication affecting cognitive and/or physical function: |
Community-dwelling | -cancer requiring treatment in the past year (except for basalioma, cancers that have been cured or carry an excellent prognosis) |
Able to walk 500 m without assistance (cane is allowed) | -severe musculoskeletal (e.g. osteoarthritis, osteoporosis with fragility fracture) disease |
-severe lung, renal or cardio-vascular disease, diabetes with insulin medication | |
Sedentary or at most moderately physically active (less than 150 min of walking/week and no regular attendance in resistance training) | -severe psychotic disorder, cognitive impairment or disease affecting cognition (e.g. Alzheimer’s disease, dementia, abnormal CERAD score), |
-serious neurological disease or disorder (e.g. Parkinson’s disease), stroke or cerebral hemorrhage with complications | |
MMSE ≥24 Informed consent to participation |
Underlying diseases likely to limit lifespan and/or intervention safety. Contraindication for physical exercise or walking tests based on ACSM41 |
Other medical, psychiatric, or behavioral factor that in the judgment of the PI and study physician may interfere with study participation or the ability to follow the intervention protocol | |
Excessive and regular use of alcohol (more than 7 units per week for women and 14 for men) | |
Difficulty in communication due to severe vision or hearing problems | |
Unable or unwilling to give informed consent or accept randomization into either study group | |
Another member of the household is a participant in PASSWORD |
MMSE Mini mental state examination test, MCI Mild cognitive impairment, ACSM American college of sports medicine