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. 2018 Sep 15;18:893. doi: 10.1186/s12885-018-4795-6

Table 1.

Association between H19 SNPs and lung cancer risks

H19 Controls (%) Cases (%) OR (95% CI) P value OR (95% CI)* P value
rs217727 CC 165(41.8) 204(36.7) 1.00(ref) 1.00(ref)
CT 172(43.5) 264(47.5) 1.241(0.937–1.644) 0.132 1.247(0.941–1.652) 0.124
TT 58(14.7) 88(15.8) 1.227(0.831–1.812) 0.303 1.229(0.832–1.816) 0.300
CT + TT vs CC 1.238(0.951–1.612) 0.113 1.243(0.954–1.618) 0.107
TT vs CT + CC 1.093(0.762–1.566) 0.630 1.092(0.762–1.565) 0.632
C allele 502(63.5) 672(60.4) 1.00(ref)
T allele 288(36.5) 440(39.6) 1.141(0.945–1.378) 0.169
rs2107425 CC 140(35.4) 161(29.0) 1.00(ref) 1.00(ref)
CT 185(46.8) 266(47.8) 1.250(0.932–1.678) 0.137 1.251(0.932–1.678) 0.136
TT 70(17.7) 129(23.2) 1.602(1.108–2.317) 0.012 1.599(1.106–2.313) 0.013
CT + TT vs CC 1.347(1.022–1.775) 0.034 1.346(1.022–1.774) 0.035
CC vs CT + TT 1.403(1.014–1.941) 0.041 1.400(1.011–1.937) 0.043
C allele 465(58.8) 588(52.9) 1.00(ref)
T allele 325(41.1) 524(47.1) 1.275(1.060–1.533) 0.010
rs2735469 CC 359(90.9) 507(91.2) 1.00(ref) 1.00(ref)
CT 36(9.1) 46(8.3) 0.905(0.573–1.428) 0.668 0.902(0.571–1.425) 0.659
TT 0(0) 3(0.5) # # # #
CT + TT vs CC 0.964(0.614–1.513) 0.873 0.962(0.613–1.510) 0.866
TT vs CC + CT # # # #
C allele 754(95.4) 1060(95.3) 1.00(ref)
T allele 36(4.6) 52(4.7) 1.027(0.665–1.588) 0.930
rs17658052 GG 371(93.9) 507(91.2) 1.00(ref) 1.00(ref)
AG 24(6.1) 47(8.5) 1.433(0.861–2.386) 0.166 1.419(0.852–2.365) 0.179
AA 0(0.0) 2(0.4) # # # #
AG + AA vs GG 1.494(0.900–2.479) 0.120 1.479(0.890–2.455) 0.131
AA vs GG + AG # # # #
G allele 766(97.0) 1061(95.4) 1.00(ref)
A allele 24(3.0) 51(4.6) 1.534(0.936–2.514) 0.087

*: adjusted by age. #: could not be calculated