Table 3.

Combined effects of H19 SNPs and cooking oil fume exposure on lung cancer risk

SNP		Oil	Controls (%)	Cases (%)	OR (95%CI)*	P value
rs217727	CC	Non-exposure	86(32.3)	59(22.0)	1(ref)
	CT + TT	Non-exposure	114(42.9)	109(40.7)	1.373(0.898–2.098)	0.143
	CC	Exposure	27(10.2)	36(13.4)	1.921(1.055–3.501)	0.033
	CT + TT	Exposure	39(14.6)	64(23.9)	2.368(1.409–3.978)	0.001
rs2107425	CC	Non-exposure	70(26.3)	43(16.0)	1(ref)
	CT + TT	Non-exposure	130(48.9)	125(46.6)	1.550(0.985–2.439)	0.058
	CC	Exposure	25(9.4)	29(10.8)	1.852(0.960–3.575)	0.066
	CT + TT	Exposure	41(15.4)	71(26.5)	2.811(1.636–4.830)	< 0.001
rs2735469	CT + TT	Non-exposure	18(6.8)	10(3.7)	1(ref)
	CC	Non-exposure	182(68.4)	158(59.0)	1.548(0.693–3.455)	0.286
	CT + TT	Exposure	9(3.4)	7(2.6)	1.388(0.395–4.876)	0.609
	CC	Exposure	57(21.4)	93(34.7)	2.906(1.253–6.744)	0.013
rs17658052	GG	Non-exposure	188(70.7)	150(56.0)	1(ref)
	GA + AA	Non-exposure	12(4.5)	18 (6.7)	1.900(0.887–4.073)	0.099
	GG	Exposure	62(23.3)	94(35.1)	1.897(1.289–2.792)	0.001
	GA + AA	Exposure	4(1.5)	6(2.2)	1.920(0.531–6.948)	0.320

*: adjusted by age