Table 5.
Measures of additive interaction between H19 SNPs and cooking oil fume exposure
| SNP | Measure | Lung cancer | Lung adenocarcinoma | ||
|---|---|---|---|---|---|
| Estimate | 95% CI | Estimate | 95% CI | ||
| rs217727 | RERI | 0.074 | −1.354-1.502 | 0.488 | −0.797-1.773 |
| AP | 0.031 | −0.566-0.628 | 0.227 | −0.326-0.780 | |
| S | 1.057 | 0.357–3.129 | 1.740 | 0.305–9.926 | |
| rs2107425 | RERI | 0.409 | −1.127-1.944 | 0.405 | −1.016-1.826 |
| AP | 0.145 | −0.374-0.665 | 0.172 | −0.401-0.744 | |
| S | 1.291 | 0.465–3.589 | 1.424 | 0.357–5.683 | |
| rs2735469 | RERI | 0.970 | −0.738-2.679 | 0.541 | −1.573-2.654 |
| AP | 0.334 | −0.262-0.930 | 0.185 | −0.588-0.929 | |
| S | 2.037 | 0.270–15.387 | 1.393 | 0.273–7.113 | |
| rs17658052 | RERI | −0.877 | −3.773-2.020 | −1.177 | −3.626-1.272 |
| AP | −0.456 | −2.468-1.555 | −0.928 | −4.045-2.189 | |
| S | 0.512 | 0.032–8.226 | 0.1864 | 0.000–244.516 | |