Table 4.
Characterization of antibody response to dengue virus serotypes using the ELISPOT-MNT50 in the studied schoolchildren population in 2010–2012 from Medellin.
| 2010 | 2011 | 2012 | Overall | |
|---|---|---|---|---|
| n=176 | n=89 | n=13 | n=278 | |
| % (n) | % (n) | % (n) | % (n) | |
|
| ||||
| Negative | 2.8 (5) | 7.9 (7) | 7.7 (1) | 4.7 (13) |
|
| ||||
| Monotypic | 26.7 (47) | 19.1 (17) | 0.0 (0) | 23.0 (64) |
| DENV1 | 4.0 (7) | 5.6 (5) | — | 4.3 (12) |
| DENV2 | 6.2 (11) | 5.6 (5) | — | 5.6 (16) |
| DENV3 | 1.1 (2) | 0.0 (0) | — | 0.7 (2) |
| DENV4 | 15.3 (27) | 7.9 (7) | — | 12.2 (34) |
|
| ||||
| Multitypic | 70.4 (124) | 73.0 (65) | 92.3 (12) | 72.3 (201) |
| DENV1/2 | 0.0 (0) | 3.4 (3) | 0.0 (0) | 1.1 (3) |
| DENV1/3 | 1.1 (2) | 0.0 (0) | 0.0 (0) | 0.7 (2) |
| DENV1/4 | 5.1 (9) | 6.7 (6) | 15.4 (2) | 6.1 (17) |
| DENV2/3 | 1.7 (3) | 0.0 (0) | 0.0 (0) | 1.1 (3) |
| DENV2/4 | 17.0 (30) | 5.6 (5) | 7.7 (1) | 12.9 (36) |
| DENV3/4 | 2.8 (5) | 0.0 (0) | 0.0 (0) | 1.8 (5) |
| DENV1/3/4 | 4.5 (8) | 1.1 (1) | 23.1 (3) | 4.3 (12) |
| DENV2/3/4 | 2.3 (4) | 0.0 (0) | 0.0 (0) | 1.4 (4) |
| DENV1/2/4 | 19.9 (35) | 22.5(20) | 7.7 (1) | 20.1 (56) |
| DENV1/2/3/4 | 15.9 (28) | 33.7 (30) | 38.5 (5) | 22.7 (63) |