Table 1.

Summary of experimental parameters

Common parameters
Pulse sequence
12 constant-current pulses
4 ms duration each
Field strength of ~150 V/cm in hind limb
10 s interval between pulses
Injection times
Therapeutic agent: 10 min post-shock
Radiotracer: 30 min post-shock
Radiotracer
99mTc pyrophosphate
Nominal injected activity: 37 ± 7.4 MBq (1.0 ± 0.2 mCi)
Image acquisition
2 min duration for each image
New image starting every 2.4 min
~3.5 h (88–90 images)
Experimental group namea	No. of rats	Shocked? (current)	Therapeutic agent
			Type	Amountb (blood concc)
0 A saline	4	No	Saline	–
0 A 17 mg poloxamer-188	3	No	Poloxamer-188	17 mg (1 mg/ml)
0.5 A saline	2	Yes (0.5 A)	Saline	–
1.0 A saline	4	Yes (1.0 A)	Saline	–
1.85 A saline	8	Yes (1.85 A)	Saline	–
1.85 A 17 mg poloxamer-188	10	Yes (1.85 A)	Poloxamer-188	17 mg (1 mg/ml)
1.85 A 68 mg poloxamer-188	4	Yes (1.85 A)	Poloxamer-188	68 mg (4 mg/ml)
1.85 A 17 mg 10 kDa dextran	10	Yes (1.85 A)	10 kDa dextran	17 mg (1 mg/ml)
1.85 A 17 mg 40 kDa dextran	14	Yes (1.85 A)	40 kDa dextran	17 mg (1 mg/ml)

^aDesignated by applied current and therapeutic agent.

^bDissolved in 0.4 ml of saline.

^cAssuming an average blood volume of 17 ml.