Table 3.

Statistical significance of fitted TAC parameters

For experimental group	Compared to	p-Valuea,b
		A	B	C
1.85 A saline	1.85 A 17 mg poloxamer-188	0.035	0.856	0.023
	1.85 A 68 mg poloxamer-188	0.271	0.569	0.912
	1.85 A 17 mg 10 kDa dextran	0.217	0.360	0.845
	1.85 A 17 mg 40 kDa dextran	0.775	0.335	0.905
	0 A 17 mg poloxamer-188	0.125	0.244	0.003
	0 A saline	0.132	0.177	0.0003
0 A saline	1.85 A 17 mg poloxamer-188	0.0003	0.544	0.0004
	1.85 A 68 mg poloxamer-188	0.006	0.036	0.0001
	1.85 A 17 mg 10 kDa dextran	0.419	0.774	0.006
	1.85 A 17 mg 40 kDa dextran	0.038	0.016	0.0002
	0 A 17 mg poloxamer-188	0.798	0.979	0.020
1.85 A 17 mg poloxamer-188	1.85 A 68 mg poloxamer-188	0.027	0.642	0.007
	1.85 A 17 mg 10 kDa dextran	0.241	0.521	0.136
	1.85 A 17 mg 40 kDa dextran	0.019	0.394	0.029
	0 A 17 mg poloxamer-188	0.0001	0.610	0.007
1.85 A 68 mg poloxamer-188	1.85 A 17 mg 10 kDa dextran	0.325	0.388	0.810
	1.85 A 17 mg 40 kDa dextran	0.274	0.847	0.833
	0 A 17 mg poloxamer-188	0.002	0.065	0.0009
1.85 A 17 mg 10 kDa dextran	1.85 A 17 mg 40 kDa dextran	0.111	0.129	0.902
	0-A 17-mg poloxamer-188	0.496	0.803	0.033
1.85 A 17 mg 40 kDa dextran	0 A 17 mg poloxamer-188	0.036	0.033	0.003

^ap-Value for Student’s t-statistic computed between the corresponding pair of fitted parameter values for the two datasets indicated.

^bBold values indicate the corresponding pair of fitted parameters is significantly different at the p < 0.01 level.