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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Exp Neurol. 2018 Jul 25;309:32–43. doi: 10.1016/j.expneurol.2018.07.013

Figure 9. Deletion of Nogo from cortical neurons via AAV2-Cre injection does not significantly affect CST sprouting.

Figure 9.

(A) tdTomato-labeled CST axons in cervical sections from Nogo+/f;tdTomato control and Nogof/f;tdTomato mice after cortical injection of AAV2-Cre and unilateral pyramidotomy. White boxes depict enlarged regions shown on the right. Scale bars = 500 μm (low mag, left), 100 μm (high mag, right). (B) Quantification of the number of tdTomatopositive axons at specific distances from the midline in the denervated side of the spinal cord normalized to the total labeled CST axon count in the medulla in Nogo+/f control (n=5) and Nogof/f (n=7) mice. n.s, not significant by two-way RM ANOVA.