Table 2. Imaging data for patients and controls.
Cardiac magnetic resonance measures for the reference controls (n=12 females) and INOCA subjects (n=22 females).
Reference Controls |
INOCA Subjects |
p value | |
---|---|---|---|
MPRI | 2.49 ± 0.41 | 1.78 ± 0.39 | < 0.0001* |
Presence of LGE | 0 | 0 | -- |
LV EF (%) | 67.7 ± 1.7 | 68.2 ± 6.2 | 0.787 |
LV ED volume (ml) | 127.5 ± 18.3 | 127.1 ± 25.4 | 0.964 |
LV ES volume (ml) | 41.2 ± 6.32 | 41.2 ± 15.5 | 0.998 |
LV stroke volume (ml) | 84.0 ± 12.4 | 85.9 ± 14.1 | 0.690 |
LV mass (g) | 74.4 ± 17.3 | 85.5 ± 21.7 | 0.136 |
LV mass index (g/m2) | 41.7 ± 7.0 | 47.1 ± 12.1 | 0.169 |
Presence of LV hypertrophy | 0 | 1 (5 %) | -- |
Cardiac output | 5.32 ± 1.21 | 5.86 ± 1.58 | 0.332 |
Systolic circumferential | −19.7 ± 2.24 | −18.3 ± 3.33 | 0.235 |
strain (%) | |||
Systolic circumferential | −94.1 ± 13.0 | −94.8 ± 19.3 | 0.919 |
strain rate (%/s) | |||
Diastolic circumferential | 126.0 ± 34.9 | 102.7 ± 29.9 | 0.055 |
strain rate (%/s) | |||
Global native | 1003.8 ± 18.5 | 1040.1 ± 29.3 | < 0.001* |
myocardial T1 (ms) | |||
Septal native | 1019.5 ± 20.8 | 1054.7 ± 30.2 | 0.001* |
myocardial T1 (ms) | |||
Resting systolic BP (mmHg) | 121.7 ± 14.3 | 128.6 ± 18.9 | 0.210 |
Resting HR (beats per minute) | 60.9 ± 10.9 | 66.9 ± 8.3 | 0.286 |
Stress HR (beats per minute) | 96.7 ± 19.1 | 92.6 ± 12.7 | 0.474 |
Resting rate-pressure product | 7409±1493 | 8623±1711 | 0.129 |
Stress rate-pressure product | 11425±2467 | 11813± 1965 | 0.629 |
indicates statistical significance.
Values are mean ± standard deviation or number (percentage).
INOCA = ischemia and no obstructive coronary artery disease; ED = end diastolic; ES = end systolic; EF = ejection fraction; LGE = late gadolinium enhancement; LV = left ventricular; MPRI = myocardial perfusion reserve index; BP = blood pressure; HR = heart rate.