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. 2018 Sep 10;9:521. doi: 10.3389/fendo.2018.00521

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Copyright © 2018 Krause, Love, Ghosh, Wang, Yun, Fukushige and Hanover.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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High levels of promoter Pol II for most O-GlcNAc marked genes do not indicate polymerase pausing. Proportional area Venn diagrams of gene set overlap among the 827 O-GlcNAc marked genes and other gene sets defined as having paused polymerase. Overlaps between the 827 O-GlcNAc marked genes (red) and genes identified as having promoter proximal paused Pol II in starved L1s from Zhong et al. (47) (n = 358, green) and active [n = 691, blue; (A)] or docked [n = 775, blue; (B)] as defined by Maxwell et al. (20). The majority of O-GlcNAc marked genes are not included in any of these gene sets previously identified as having promoter proximal Pol II in starved conditions in wild type animals.