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. 2018 Sep 10;9:1276. doi: 10.3389/fphys.2018.01276

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Copyright © 2018 Fujiwara, Hermann-Luibl, Katsura, Sekiguchi, Ida, Helfrich-Förster and Yoshii.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CCHa1 affects morning activity peak and total activity level. (A) Representative actograms of w control, CCHa1 mutant (CCHa1^SK8), UAS control (+>CCHa1^RNAi), and CCHa1 knockdown (tim > CCHa1^RNAi) strains. (B) Mean total activity levels (±SEM) in LD and DD. (C) Average activity profiles of CCHa1 mutants and CCHa1 knockdown flies. The daily average activity for each strain was calculated from the last 3 days of LD. All activity profiles were normalized to 1. (D) Mean siesta durations (±SEM) of CCHa1 mutants and CCHa1 knockdown flies. Numbers in the columns indicate the number of flies. One-way ANOVA with Tukey’s multiple comparison test after the Kolmogorov–Smirnov test; ^∗p < 0.05, ^∗∗p < 0.01.